Villalstonine_product_DataBase

Bioactivity	Villalstonine is a bisindole alkaloid with various biological activities including anticancer, antimalarial, and antiamoebic activities. Villalstonine exhibits potent antiplasmodial activity against the multidrug-resistant K1 strain of P. falciparum with an IC50 value of 0.27 μM[1].
Invitro	Villalstonine ((+)-Villalstonine；化合物 43) 对 KB 细胞具有细胞毒性，ED50 值为 11.6 μM[1]。 Villalstonine 对恶性疟原虫 T9-96 株也具有很强的抗性，IC50 值为 0.94 μM[1]。Villalstonine 还对 HT-29 细胞系表现出抗癌活性，ED50 值为 8.0 μM。此外，Villalstonine 对长春新碱 (HY-N0488) 耐药的 KB/VJ300 细胞具有细胞毒性，IC50 值为 0.42 μg/mL (μM)[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Villalstonine 相关抗体:
CAS	2723-56-0
Formula	C42H50N4O4
Molar Mass	674.87
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Kamal P Pandey, et al. Bisindole Alkaloids from the Alstonia Species: Recent Isolation, Bioactivity, Biosynthesis, and Synthesis. Molecules. 2021 Jun 7;26(11):3459.

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