| Bioactivity | Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1]. | ||||||||||||
| Invitro | Vildagliptin promotes beta cell survival by inhibiting cell apoptosis. Vildagliptin also promotes cell proliferation[2]. | ||||||||||||
| Name | Vildagliptin | ||||||||||||
| CAS | 274901-16-5 | ||||||||||||
| Formula | C17H25N3O2 | ||||||||||||
| Molar Mass | 303.40 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|