| Bioactivity | Verticilide is a ryanodine-binding inhibitor and inhibits ryanodine binding to ryanodine receptors in the cockroach at an IC50 value of 4.2 ?μM (whereas inhibition against mouse ryanodine receptors was weak (IC50=53.9?μM))[1]. |
| Name | Verticilide |
| CAS | 693778-57-3 |
| Sequence | cyclo[N(Me)Ala-D-ONle(Me)-N(Me)Ala-D-ONle(Me)-N(Me)Ala-D-ONle(Me)-N(Me)Ala-D-ONle(Me)] |
| Formula | C44H76N4O12 |
| Molar Mass | 853.09 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kazuro Shiomi, et al. Verticilide, a new ryanodine-binding inhibitor, produced by Verticillium sp. FKI-1033. J Antibiot (Tokyo). 2010 Feb;63(2):77-82. |
Verticilide
CAS: 693778-57-3 F: C44H76N4O12 W: 853.09
Verticilide is a ryanodine-binding inhibitor and inhibits ryanodine binding to ryanodine receptors in the cockroach at a
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.