| Bioactivity | Verinurad (RDEA3170) is a highly potent and specific URAT1 inhibitor with an IC50 of 25 nM[1]. | ||||||||||||
| Target | IC50: 25 nM (URAT1) | ||||||||||||
| Invitro | Verinurad inhibits the transport activity of human URAT1 in a dose-dependent manner, at high potency with an IC50 of 25 nM [1]. | ||||||||||||
| Name | Verinurad | ||||||||||||
| CAS | 1352792-74-5 | ||||||||||||
| Formula | C20H16N2O2S | ||||||||||||
| Molar Mass | 348.42 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Tan PK, et al. Discovery and characterization of verinurad, a potent and specific inhibitor of URAT1 for the treatment of hyperuricemia and gout. Sci Rep. 2017 Apr 6;7(1):665. |