| Bioactivity | Velaglucerase alfa is produced through gene activation technology and is identical to wild-type enzyme. Velaglucerase alfa targets accumulated glucocerebroside primarily within the lysosome of the macrophages in the affected organs and systems. Velaglucerase alfa is an enzyme replacement therapy (ERT) for type 1 Gaucher disease (GD)[1]. |
| Invitro | Velaglucerase alfa 是通过基因激活技术生产的，与野生型酶相同。Velaglucerase alfa 主要针对受累器官和系统中巨噬细胞溶酶体内累积的葡萄糖脑苷脂。Velaglucerase alfa 是 1 型戈谢病 (GD) 的一种酶替代疗法 (ERT)[1]。 |
| Name | Velaglucerase alfa |
| CAS | 884604-91-5 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Morris JL. Velaglucerase alfa for the management of type 1 Gaucher disease. Clin Ther. 2012 Feb;34(2):259-71. |