Val-Arg-Pro-DL-Arg-Fluoromethylketone_product_DataBase

Bioactivity	Val-Arg-Pro-DL-Arg-Fluoromethylketone is a potent MALT1 inhibitor. Val-Arg-Pro-DL-Arg-Fluoromethylketone inhibits cell proliferation and migration. Val-Arg-Pro-DL-Arg-Fluoromethylketone shows anticancer activity[1].
Target	MALT1
Invitro	Val-Arg-Pro-DL-Arg-Fluoromethylketone (75 mol/L; 6, 12, 24, 36, and 48 h) 抑制 OCI-LY10 细胞的增殖和迁移[1]。 Cell Proliferation Assay[1] Cell Line:
In Vivo	Val-Arg-Pro-DL-Arg-Fluoromethylketone (37.5 M*0.2 mL；每隔一天，持续 12 天) 抑制小鼠肿瘤的生长[1]。 Animal Model:
Name	Val-Arg-Pro-DL-Arg-Fluoromethylketone
CAS	1926163-57-6
Sequence	Val-Arg-Pro-{DL-Arg}-{Fluoromethylketone}
Shortening	VRP-{DL-Arg}-{Fluoromethylketone}
Formula	C31H49FN10O6
Molar Mass	676.78
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Feng J, et al. Z-VRPR-FMK can inhibit the growth and invasiveness of diffuse large B-cell lymphoma by depressing NF-κB activation and MMP expression induced by MALT1. Int J Clin Exp Pathol. 2019 Jun 1;12(6):1947-1955.

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