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Val-Ala-PABC-Exatecan trifluoroacetate

CAS: 2928571-45-1 F: C42H44F4N6O10 W: 868.83

Val-Ala-PABC-Exatecan trifluoroacetate is a Drug-Linker Conjugates for ADC,consiting of a cleavable Tesirine linker (Va
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Bioactivity Val-Ala-PABC-Exatecan trifluoroacetate is a Drug-Linker Conjugates for ADC,consiting of a cleavable Tesirine linker (Val-Ala-PABC) and Exatecan (topoisomerase I inhibitor,HY-13631). Val-Ala-PABC-Exatecan trifluoroacetate can be used for ADC molecues synthesis,such as Mal-PEGn-amide-va-Exatecan[1].
Name Val-Ala-PABC-Exatecan trifluoroacetate
CAS 2928571-45-1
Formula C42H44F4N6O10
Molar Mass 868.83
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Cheng X, et al. MORAb-202, an Antibody-Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity. Mol Cancer Ther. 2018 Dec;17(12):2665-2675.