Bioactivity | Val-Ala-PABC-Exatecan trifluoroacetate is a Drug-Linker Conjugates for ADC,consiting of a cleavable Tesirine linker (Val-Ala-PABC) and Exatecan (topoisomerase I inhibitor,HY-13631). Val-Ala-PABC-Exatecan trifluoroacetate can be used for ADC molecues synthesis,such as Mal-PEGn-amide-va-Exatecan[1]. |
Name | Val-Ala-PABC-Exatecan trifluoroacetate |
CAS | 2928571-45-1 |
Formula | C42H44F4N6O10 |
Molar Mass | 868.83 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Cheng X, et al. MORAb-202, an Antibody-Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity. Mol Cancer Ther. 2018 Dec;17(12):2665-2675. |