| Bioactivity | Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes with MIC values of 6 µg/mL. Vaccarin C also has high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines with CTC50 values of 3.35 and 5.72 μmol/L, respectively[1]. |
| CAS | 177602-12-9 |
| Sequence | Cyclo(Gly-Tyr-Val-Pro-Leu-Trp-Pro) |
| Shortening | Cyclo(GYVPLWP) |
| Formula | C43H56N8O8 |
| Molar Mass | 812.95 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dahiya R, et al. Synthesis and pharmacological investigation of segetalin C as a novel antifungal and cytotoxic agent. Arzneimittelforschung. 2008;58(1):29-34. |
Vaccarin C
CAS: 177602-12-9 F: C43H56N8O8 W: 812.95
Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophyt
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