Bioactivity | Vabametkib is a potent inhibitor of hepatocyte growth factor receptor (HGFR). Vabametkib inhibits Hs746T cells proliferation and inhibits c-Met with an IC50 value of 7 nM. Vabametkib can be used as an antineoplastic agent[1][2]. |
Name | Vabametkib |
CAS | 1571903-56-4 |
Formula | C29H34N12O |
Molar Mass | 566.66 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. WHO Drug Informat ion - World Health Organization (WHO). [2]. Jung Hui Jeong, et al. Preparation of triazolopyrazine derivatives as c-Met kinase inhibitors: Korea, Republic of, KR2014022229. 2014-02-24. [3]. WHO Drug Information-World Health Organization (WHO). |