| Bioactivity | VU6043653 is a potent, selective and cross the blood-brain barrier metabotropic glutamate receptor subtype 5 (mGlu5) negative allosteric modulator with an IC50 value of 325 nM for h mGlu5[1]. |
| CAS | 3032791-06-0 |
| Formula | C16H14FN5O2 |
| Molar Mass | 327.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Elizabeth S. Childress, et al. Discovery of 4-(5-Membered)Heteroarylether-6-methylpicolinamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5. ACS Med. Chem. Lett. 2024. |
VU6043653
CAS: 3032791-06-0 F: C16H14FN5O2 W: 327.31
VU6043653 is a potent, selective and cross the blood-brain barrier metabotropic glutamate receptor subtype 5 (mGlu5) neg
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