| Bioactivity | VU6036720 is a potent and specific in vitro inhibitor of Kir4.1/5.1. VU6036720 can inhibit Kir4.1/5.1 channels with an IC50 value of 0.24 μM. VU6036720 can be used for the research of brain and kidney[1]. |
| Invitro | VU6036720 can inhibit Kir4.1/5.1 channels with an IC50 value of 0.24 μM[1].VU6036720 inhibits Kir4.1/5.1 activity through a reduction of channel open-state probability and single-channel current amplitude[1]. |
| Name | VU6036720 |
| Formula | C20H22ClFN4O2S |
| Molar Mass | 436.93 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Samantha J McClenahan, et al. VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels. Mol Pharmacol. 2022 May;101(5):357-370. |