| Bioactivity | VU6001966 (compound 15m) is a potent and cross the blood-brain barrier mGlu2 (metabotropic glutamate receptor 2) negative allosteric modulator with IC50s of 78 nM and >30 µM for mGlu2 and mGlu3, respectively. VU6001966 can serve as an mGlu2 PET tracer[1]. |
| Name | VU6001966 |
| CAS | 2009052-76-8 |
| Formula | C17H15FN4O2 |
| Molar Mass | 326.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bollinger KA,et al. Design and Synthesis of mGlu2 NAMs with Improved Potency and CNS Penetration Based on a Truncated Picolinamide Core. ACS Med Chem Lett. 2017 Aug 3;8(9):919-924. |
VU6001966
CAS: 2009052-76-8 F: C17H15FN4O2 W: 326.33
VU6001966 (compound 15m) is a potent and cross the blood-brain barrier mGlu2 (metabotropic glutamate receptor 2) negativ
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.