| Bioactivity | VU0530244 is a potent antagonist of 5-HT2B, with the IC50 of 17.3 nM. VU0530244 is predicted to have very limited potential for brain penetration in human subjects, as both are predicted to be substrates for P-gp-mediated efflux in humans[1]. |
| CAS | 1396886-30-8 |
| Formula | C22H20FN5O |
| Molar Mass | 389.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Aaron M Bender, et al. Identification of Potent, Selective, and Peripherally Restricted Serotonin Receptor 2B Antagonists from a High-Throughput Screen. Assay Drug Dev Technol. 2023 Apr;21(3):89-96. |
VU0530244
CAS: 1396886-30-8 F: C22H20FN5O W: 389.43
VU0530244 is a potent antagonist of 5-HT2B, with the IC50 of 17.3 nM. VU0530244 is predicted to have very limited potent
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