Bioactivity | VU0431316 is a potent and selective non-competitive antagonist of mGlu5 with an IC50 value of 24nM[1]. |
CAS | 1620203-63-5 |
Formula | C14H9ClN6O2 |
Molar Mass | 328.71 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Brittney S Bates, et al. Discovery of VU0431316: a negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3307-14. |