| Bioactivity | VU0410425 is an mGlu1 negative allosteric modulator. VU0410425 exhibits potent inhibitory activity for rat mGlu1 with an IC50 value of 140 nM. VU0410425 can be used for the research of central nervous system disorders[1]. |
| Target | IC50: 140 nM (rat mGlu1) |
| Invitro | VU0410425 对大鼠 mGlu1 表现出有效的抑制活性，IC50 值为 140 nM，但对人 mGlu1 无活性[1]。 |
| Name | VU0410425 |
| CAS | 1341167-72-3 |
| Formula | C19H16ClN3O3 |
| Molar Mass | 369.80 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cho HP, et al. A novel class of succinimide-derived negative allosteric modulators of metabotropic glutamate receptor subtype 1 provides insight into a disconnect in activity between the rat and human receptors. ACS Chem Neurosci. 2014;5(7):597-610. |
VU0410425
CAS: 1341167-72-3 F: C19H16ClN3O3 W: 369.80
VU0410425 is an mGlu1 negative allosteric modulator. VU0410425 exhibits potent inhibitory activity for rat mGlu1 with an
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.