Bioactivity | VU0364739 is a selective PLD2 inhibitor (IC50: 22 nM). VU0364739 decreases cancer cell proliferation[1]. | ||||||||||||
Target | PLD | ||||||||||||
Name | VU0364739 | ||||||||||||
CAS | 1244639-78-8 | ||||||||||||
Formula | C26H27FN4O2 | ||||||||||||
Molar Mass | 446.52 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Lavieri RR, et al. Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor. J Med Chem. 2010 Sep 23;53(18):6706-19. |