| Bioactivity | VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) agent. VP-4604 exhibits significant microbial growth inhibition toward Staphylococcus aureus (ATCC 43300) with MIC of 4-8 µg/mL. VP-4604 inhibits the growth of methicillin‐resistant Staphylococcus aureus with growth inhibition >95%[1]. |
| Invitro | VP-4604 (2.5 mM, 18 hours) inhibits drug-resistant S. aureus and P. aeruginosa with growth inhibiton (%) GI >95%[1].VP-4604 shows low cytotoxicity with a CC50 value >118.4 mM towards HEK-293 (human embryonic kidney) ATCC CRL‐1573 and an HC10 vaule >118.4 μM towards RBC (human red blood cells) [1].VP-4604 (2.5 mM) is tolerated by mammalian cells (HaCaT, lymphocytes) with the inhibition growth (%) of 44.1% and >50%, respectively[1]. Cell Proliferation Assay[1] Cell Line: |
| Name | VP-4604 |
| CAS | 64268-93-5 |
| Formula | C11H14N2O4S |
| Molar Mass | 270.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |