Bioactivity | VEGFR2-IN-4 (compound 25) is a potent and selective VEGFR2 kinase inhibitor, with a GI50 of 0.7 nM. VEGFR2-IN-4 shows anti-angiogenic effect. VEGFR2-IN-4 can be used for the research of rheumatoid arthritis[1]. |
Name | VEGFR2-IN-4 |
Formula | C23H20N4O3S |
Molar Mass | 432.49 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chen Q, et, al. Discovery of highly potent and selective VEGFR2 kinase inhibitors for the treatment of rheumatoid arthritis. Eur J Med Chem. 2023 Sep 5;257:115456. |