VEGFR-2/c-Met-IN-2

CAS: F: C22H15ClN4O3S W: 450.90

VEGFR-2/c-Met-IN-2 (compound 3e) is a VEGFR-2/c-Met inhibitor, with IC50 values of 83 and 48 nM, respectively. VEGFR-2/c

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Bioactivity	VEGFR-2/c-Met-IN-2 (compound 3e) is a VEGFR-2/c-Met inhibitor, with IC50 values of 83 and 48 nM, respectively. VEGFR-2/c-Met-IN-2 exhibits cytotoxic activity against HCT-116 cell line (IC50: 3.403 µM)[1].
Invitro	VEGFR-2/c-Met-IN-2 (compound 3e) 对结直肠癌细胞的选择性细胞毒性是正常细胞的 3 倍以上[1]。 0 --> VEGFR-2/c-Met-IN-2 相关抗体:
Name	VEGFR-2/c-Met-IN-2
Formula	C22H15ClN4O3S
Molar Mass	450.90
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Hassan A, et al. Novel 3-phenylquinazolin-2,4(1H,3H)-diones as dual VEGFR-2/c-Met-TK inhibitors: design, synthesis, and biological evaluation. Sci Rep. 2023 Oct 30;13(1):18567.

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