Bioactivity | VEGFR-2/c-Met-IN-1 is a dual inhibitoe of VEGFR-2 and c-Met with IC50s of 138 nM and 74 nM, respectively. VEGFR-2/c-Met-IN-1 has antitumor activity[1]. |
Name | VEGFR-2/c-Met-IN-1 |
Formula | C23H16N4O5S |
Molar Mass | 460.46 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Abdelfattah Hassan, et al. Novel 3-phenylquinazolin-2,4(1H,3H)-diones as dual VEGFR-2/c-Met-TK inhibitors: design, synthesis, and biological evaluation.Sci Rep. 2023 Oct 30;13(1):18567. |