| Bioactivity | VEGFR-2-IN-39, a PROTAC, displays potent inhibitory activity against VEGFR-2. VEGFR-2-IN-39 concentration-dependently inhibited proliferation of human umbilical vein endothelial cells (HUVECs) with IC50 of 32.793 µM[1]. |
| Name | VEGFR-2-IN-39 |
| CAS | 2353417-86-2 |
| Formula | C55H66FN9O6S |
| Molar Mass | 1000.23 |
| Appearance | 固体 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Shan Y, et al. Discovery of novel anti-angiogenesis agents. Part 11: Development of PROTACs based on active molecules with potency of promoting vascular normalization. Eur J Med Chem. 2020 Nov 1;205:112654. |
VEGFR-2-IN-39
CAS: 2353417-86-2 F: C55H66FN9O6S W: 1000.23
VEGFR-2-IN-39, a PROTAC, displays potent inhibitory activity against VEGFR-2. VEGFR-2-IN-39 concentration-dependently in
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