| Bioactivity | VEGFR-2-IN-19 (Compound 15b) is a potent VEGFR2 inhibitor. VEGFR-2-IN-19 induces cell apoptosis and increases intracellular reactive oxygen species level. VEGFR-2-IN-19 can be used as an anticancer agent[1]. |
| Invitro | VEGFR-2-IN-19 (Compound 15b) (0-100 µM, 48 h) shows antiproliferative activity against cancer cells[1].VEGFR-2-IN-19 (0-10 µM, 48 h) inhibits the phosphorylation of VEGFR2 and the Raf/MEK/ERK signaling pathway, induces cell apoptosis, and arrests cell cycle at G0/G1 phase in HT-29 cells[1].VEGFR-2-IN-19 (0-10 µM, 12 h) increases intracellular reactive oxygen species level in HT-29 cells[1]. Cell Cytotoxicity Assay[1] Cell Line: |
| Name | VEGFR-2-IN-19 |
| CAS | 2456315-41-4 |
| Formula | C21H19N3O2 |
| Molar Mass | 345.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
VEGFR-2-IN-19
CAS: 2456315-41-4 F: C21H19N3O2 W: 345.39
VEGFR-2-IN-19 (Compound 15b) is a potent VEGFR2 inhibitor. VEGFR-2-IN-19 induces cell apoptosis and increases intracellu
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.