Bioactivity | VCP Activator 1 is a VCP activator that dose-dependently stimulates VCP ATPase activity. VCP Activator 1 binds an allosteric pocket near the C-terminus. In addition, VCP Activator 1 binding site can also be occupied by a phenylalanine residue in the VCP C-terminal tail[1]. |
Name | VCP Activator 1 |
Formula | C20H22N2O2S |
Molar Mass | 354.47 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jones NH, et al. Allosteric activation of VCP, a AAA unfoldase, by small molecule mimicry. bioRxiv [Preprint]. 2023 Oct 2:2023.10.02.560478. |