| Bioactivity | VCC972839:01 is an inhibitor for cyclin dependent kinase (CDK9), with IC50 of 7 nM. VCC972839:01 inhibits the cell viability of SCLC cells in nanomolar levels. VCC972839:01 induces apoptosis through an intrinsic pathway. VCC972839:01 exhibits antitumor activity in mouse model[1]. |
| Formula | C24H20N6O |
| Molar Mass | 408.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Valdez Capuccino L, et al., CDK9 inhibition as an effective therapy for small cell lung cancer. Cell Death Dis. 2024 May 20;15(5):345. |