| Bioactivity | Urotensin II (114-124), human TFA, an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14. | ||||||
| Invitro | Human Urotensin II (U-II) binds to recombinant human GPR14 with high affinity, and the binding is functionally coupled to calcium mobilization. Human Urotensin II induces concentration-dependent increases in intracellular calcium in a HEK-293 cell line expressing human GPR14 (EC50=0:62±0.17 nM, n=6)[1]. | ||||||
| Name | Urotensin II (114-124), human TFA | ||||||
| Sequence | Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val (Disulfide bridge: Cys5-Cys7) | ||||||
| Shortening | ETPDCFWKYCV (Disulfide bridge: Cys5-Cys7) | ||||||
| Formula | C66H86F3N13O20S2 | ||||||
| Molar Mass | 1502.59 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Urotensin II (114-124), human TFA
CAS: F: C66H86F3N13O20S2 W: 1502.59
Urotensin II (114-124), human TFA, an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orp
Data collection：peptidedb@qq.com
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