| Bioactivity | ACTH (4-11), an adrenocorticotropin hormone fragment, possesses a weak α-melanocyte stimulating hormone (α-MSH) potency only at high doses (100 and 1000 nM). |
| Invitro | α-melanocyte stimulating hormone (MSH) induces the differentiation of mouse epidermal melanocytes in vivo and in vitro. Adrenocorticotropic hormone (ACTH) possesses the same amino acid sequence as MSH does. α-MSH induces the differentiation of mouse epidermal melanocytes in vivo and in vitro. ACTH (4-11) loses almost all activity for the binding to melanocortin receptor 1 (MC1R)[1]. |
| Name | ACTH (4-11) |
| CAS | 67224-41-3 |
| Sequence | Met-Glu-His-Phe-Arg-Trp-Gly-Lys |
| Shortening | MEHFRWGK |
| Formula | C50H71N15O11S |
| Molar Mass | 1090.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |