| Bioactivity | Uroguanylin (human) is a natural ligand for the Guanylyl Cyclase (GCC) receptor expressed in metastatic colorectal cancer tumors. Uroguanylin (human) has anti-tumor actions in an animal model for human colon cancer[1][2]. |
| Name | Uroguanylin (human) |
| CAS | 154525-25-4 |
| Sequence | Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu (Disulfide bridge: Cys4-Cys12,Cys7-Cys15) |
| Shortening | NDDCELCVNVACTGCL (Disulfide bridge: Cys4-Cys12,Cys7-Cys15) |
| Formula | C64H102N18O26S4 |
| Molar Mass | 1667.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lewis DK, et al. Hypertrehalosemic hormone in a cockroach: molecular cloning and expression. Mol Cell Endocrinol. 1997;130(1-2):101-108. |