| Bioactivity | Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III (human) preferentially binds and activates CRF-R2 and has a discrete central nervous system and peripheral distribution. Urocortin III (human) selectively binds to type 2 CRF receptors with Ki values of 13.5, 21.7, and >100 nM for mCRF2β, rCRF2α, and hCRF1, respectively. Urocortin III (human) mediates somatostatin-dependent negative feedback control of Insulin (human) (HY-P0035) secretion[1][2]. |
| Invitro | Urocortin III (human) (20 分钟；稳定表达克隆人 CRF-R1 或鼠 CRF-R2 的 CHO 细胞) 诱导细胞内 cAMP 积累[1]。 |
| Name | Urocortin III (human) |
| CAS | 357952-09-1 |
| Shortening | FTLSLDVPTNIMNLLFNIAKAKNLRAQAAANAHLMAQI-NH2 |
| Formula | C185H307N53O50S2 |
| Molar Mass | 4137.93 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Urocortin III (human)
CAS: 357952-09-1 F: C185H307N53O50S2 W: 4137.93
Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III (human) preferentially bi
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