| Bioactivity | Urocortin II, mouse is a potent and selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2) receptor with Ki values of 0.66 nM and ﹥100 nM for CRFR2 and CRFR1, respectively. Urocortin II, mouse activates CRF2 receptors in a cAMP/PKA- and Ca2+/CaMKII-dependent manner.Urocortin II, mouse is expressed in discrete areas of the central nervous system, and activates central neurons involved in the processing of visceral sensory information, and in modulating autonomic outflow[1][2][3]. |
| Invitro | Urocortin II, mouse 通过激活 CRF2 受体在小鼠心室肌细胞中引起正性肌力和正性变性作用[1]。Urocortin II, mouse 通过以 cAMP/PKA 和 Ca2+/CaMKII 依赖性方式激活 CRF2 受体[1]。 |
| Name | Urocortin II, mouse |
| CAS | 330648-32-3 |
| Shortening | VILSLDVPIGLLRILLEQARYKAARNQAATNAQILAHV-NH2 |
| Formula | C187H320N56O50 |
| Molar Mass | 4152.96 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Urocortin II, mouse
CAS: 330648-32-3 F: C187H320N56O50 W: 4152.96
Urocortin II, mouse is a potent and selective endogenous peptide agonist of type-2 corticotropin-releasing factor (CRF2)
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