| Bioactivity | Urease-IN-5 is an inhibitor of urease with an IC50 value of 1.473 µM. Urease-IN-5 has low cytotoxicity and inhibitory activity on P. vulgaris with an IC50 value of 17.78 µg/mL[1]. |
| Target | IC50: 1.473 µM (Urease) |
| Invitro | Urease-IN-5 (Compound 6i) (100 µM；72 h) 对 MOLT-4 细胞活力无显著影响，此时细胞存活率为 97.8 %[1]。 Cell Viability Assay[1] Cell Line: |
| Name | Urease-IN-5 |
| Formula | C16H20N2O3S |
| Molar Mass | 320.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dastyafteh N, et al. New thioxothiazolidinyl-acetamides derivatives as potent urease inhibitors: design, synthesis, in vitro inhibition, and molecular dynamic simulation. Sci Rep. 2023 Jan 2;13(1):21. |