| Bioactivity | Urease-IN-4 is an effective inhibitor of urease with an IC50 value of 1.64 µM. Urease-IN-4 has low cytotoxicity and shows inhibitory activity on P. vulgaris with an IC50 value of 15.27 µg/mL[1]. |
| Target | IC50: 1.64 µM (Urease) |
| Invitro | Urease-IN-4 (Compound 6e) (100 µM；72 h) 对 MOLT-4 细胞活力无显著影响，此时细胞存活率为 91.7 %[1]。 Cell Viability Assay[1] Cell Line: |
| Name | Urease-IN-4 |
| Formula | C16H20N2O3S |
| Molar Mass | 320.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dastyafteh N, et al. New thioxothiazolidinyl-acetamides derivatives as potent urease inhibitors: design, synthesis, in vitro inhibition, and molecular dynamic simulation. Sci Rep. 2023 Jan 2;13(1):21. |