Bioactivity | Urease-IN-18 (compound 13a) is an uncompetitive urease inhibitor with an IC50 value of 1.6 μM. Urease helps maintain an alkaline environment favorable for the survival and proliferation of specific pathogens within the host[1]. |
Formula | C30H27N5O5 |
Molar Mass | 537.57 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hassan Sepehrmansourie, et al. Novel coumarin-based acetohydrazide-1,2,3-triazole derivatives as urease enzyme inhibitors: Synthesis, in vitro evaluation, and molecular dynamics simulation studies. |