| Bioactivity | Urantide is a selective and competitive urotensin-II (UT) receptor antagonist peptide (pKB=8.3) that blocks human urotensin-II (hU-II)-induced contractions in rat thoracic aorta ex vivo. Urantide can be used to study the (patho)physiological role of hU-II in the mammalian cardiovascular system[1]. |
| Target | urotensin-II Receptor (UT Receptor). |
| CAS | 669089-53-6 |
| Shortening | D-{Pen}-F-{d-Trp}-{Orn}-YCV (Disulfide bridge: Cys2-Cys7) |
| Formula | C51H66N10O12S2 |
| Molar Mass | 1075.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Patacchini R, et al. Urantide TFA: an ultrapotent urotensin II antagonist peptide in the rat aorta. Br J Pharmacol. 2003 Dec;140(7):1155-8. |
Urantide
CAS: 669089-53-6 F: C51H66N10O12S2 W: 1075.26
Urantide is a selective and competitive urotensin-II (UT) receptor antagonist peptide (pKB=8.3) that blocks human uroten
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