Bioactivity | Upadacitinib (Standard) is the analytical standard of Upadacitinib. Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research. |
CAS | 1310726-60-3 |
Formula | C17H19F3N6O |
Molar Mass | 380.37 |
Appearance | 固体 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |