Bioactivity | Udenafil (DA8159) is a potent, selective and orally active phosphodiesterase type 5 (PDE5) inhibitor. Udenafil also inhibits cGMP hydrolysis and can be used for erectile dysfunction research[1][2]. | ||||||||||||
Invitro | Udenafil is an oral PDE5 inhibitor. Udenafil significantly increases cAMP and cGMP levels and are more highly distributed in the prostate than plasma[1]. | ||||||||||||
Name | Udenafil | ||||||||||||
CAS | 268203-93-6 | ||||||||||||
Formula | C25H36N6O4S | ||||||||||||
Molar Mass | 516.66 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Paick, J.S., et al., The efficacy and safety of udenafil, a new selective phosphodiesterase type 5 inhibitor, in patients with erectile dysfunction. J Sex Med, 2008. 5(4): p. 946-53. [2]. Zhao, C., et al., Activity of phosphodiesterase type 5 inhibitors in patients with lower urinary tract symptoms due to benign prostatic hyperplasia. BJU Int, 2011. 107(12): p. 1943-7. |