| Bioactivity | USP8-IN-3 (Compd U51) is a deubiquitinase USP8 inhibitor with an IC50 value of 4.0 μM. USP8-IN-3 also inhibits the proliferation of GH3 and H1957 cells with GI50s of 37.03 μM and 6.01 μM, respectively[1]. | ||||||||||||
| Invitro | USP8-IN-3 (6.25-100 μM; 15 min) 抑制 USP8 对二聚泛素的剪切活性[1]。 Western Blot Analysis[1] Cell Line: | ||||||||||||
| Name | USP8-IN-3 | ||||||||||||
| CAS | 2477651-10-6 | ||||||||||||
| Formula | C18H18F3N5O2S | ||||||||||||
| Molar Mass | 425.43 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Li zhiyun, et al. Preparing method and application of USP8 inhibitor: China, CN111138358 A. 2020-05-12. |
USP8-IN-3
CAS: 2477651-10-6 F: C18H18F3N5O2S W: 425.43
USP8-IN-3 (Compd U51) is a deubiquitinase USP8 inhibitor with an IC50 value of 4.0 μM. USP8-IN-3 also inhibits the prol
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