USP7-IN-12_product_DataBase

CAS: 2763698-01-5 F: C29H28ClFN4O2S W: 551.07

USP7-IN-12 (compound 1) is a potent and orally active Usp7 inhibitor with an IC50 value of 3.67 nM. USP7-IN-12 shows ant

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	USP7-IN-12 (compound 1) is a potent and orally active Usp7 inhibitor with an IC50 value of 3.67 nM. USP7-IN-12 shows antiproliferative activity[1].
Invitro	USP7-IN-12 (compound 1) (72 h) 显示出抗增殖活性，对 RS4；11 的 IC50 值为 69.5 nM[1]。
In Vivo	USP7-IN-12 (5 mg/kg；口服) 在雄性 SD 大鼠中显示出良好的药代动力学数据，T1/2 为 3.68 h、Tmax 3.33 h、Cmax 330 ng/mL 和 AUC0-inf OF 2014 hr*ng/mL[1]。
Name	USP7-IN-12
CAS	2763698-01-5
Formula	C29H28ClFN4O2S
Molar Mass	551.07
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Deng Hou, et al. Usp7 inhibitor. WO2022048498A1.

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