| Bioactivity | USP1-IN-3 is a selective USPI inhibitor. USP1-IN-3 inhibits USPI-UAFI with an IC50 value of ＜30 nM. USP1-IN-3 can be used for the research of cancer[1]. |
| Target | IC50: ＜30 nM (USPI-UAFI) |
| Invitro | USP1-IN-3 has inhibitory against USPI-UAFI with an IC50 value of ＜30 nM[1].USP1-IN-3 has viability for a non-isogenic pair of BRCAI mutant and BRCAI WT cell lines with IC50 values of ＜100 nM and ＞ 10 μM, respectively[1]. |
| Name | USP1-IN-3 |
| CAS | 2821749-58-8 |
| Formula | C27H24F3N7O |
| Molar Mass | 519.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Scott Throner, et al. Pyrrolo[3,2-d]pyrimidine compounds and methods of use in the treatment of cancer. Patent. WO2022174184A1. |
USP1-IN-3
CAS: 2821749-58-8 F: C27H24F3N7O W: 519.52
USP1-IN-3 is a selective USPI inhibitor. USP1-IN-3 inhibits USPI-UAFI with an IC50 value of ＜30 nM. USP1-IN-3 can be us
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