| Bioactivity | URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM. URAT1 inhibitor 1 has potential to treat hyperuricemia associated with gout[1]. | ||||||||||||
| Target | IC50: 32 nM (URAT1). | ||||||||||||
| Name | URAT1 inhibitor 1 | ||||||||||||
| CAS | 2268720-62-1 | ||||||||||||
| Formula | C19H15Br2N5O2S2 | ||||||||||||
| Molar Mass | 569.29 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Wu JW, et al. Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout. Bioorg Med Chem Lett. 20 |