Bioactivity | UR-MB-355, a GPR3 ligand, binds to GPR3 and closely related receptors, GPR6 and GPR12, with similar submicromolar affinities[1]. |
Target | pEC50:6.05 (at Nluc-GPR3). |
Invitro | UR-MB-355 是 GPR3 的一个配体,与GPR3和密切相关的受体 GPR6 和 GPR12 结合,具有相似的亚微摩尔亲和力。 0 --> UR-MB-355 相关抗体: |
Name | UR-MB-355 |
Formula | C54H54ClF3N8O8 |
Molar Mass | 1035.50 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Merlin Bresinsky, et al. Development of Fluorescent AF64394 Analogues Enables Real-Time Binding Studies for the Orphan Class A GPCR GPR3. J Med Chem. 2023 Nov 9;66(21):15025-15041. |