Bioactivity | UP158 enhances the activity of ATPase, and activates valosin-containing protein (VCP) with an EC50 of 2.57 μM[1]. |
CAS | 489402-33-7 |
Formula | C17H17ClN4O2 |
Molar Mass | 344.80 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Phan JM, et al., VCP activator reverses nuclear proteostasis defects and enhances TDP-43 aggregate clearance in multisystem proteinopathy models. J Clin Invest. 2024 May 23;134(14):e169039. |