| Bioactivity | UNC9975 is a D2R agonist that displays signaling bias via β-arrestin–ergic signaling and a simultaneously antagonist of Gi-regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9975 can be utilized in antipsychotic research[1]. |
| CAS | 1354030-19-5 |
| Formula | C23H28Cl2N4O2 |
| Molar Mass | 463.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Allen JA, et al. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18488-93. |
UNC9975
CAS: 1354030-19-5 F: C23H28Cl2N4O2 W: 463.40
UNC9975 is a D2R agonist that displays signaling bias via β-arrestin–ergic signaling and a simultaneously antagonist o
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.