| Bioactivity | UNC10142 (Compound 44) is a first-in-class small molecule antagonist of CHD1 that binds with an IC50 value of 1.7 μM. UNC10142 leads to a dose-dependent reduction in viability in PTEN-deficient prostate cancer cells[1]. |
| Formula | C33H52N6O3 |
| Molar Mass | 580.80 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Johnson RL, et al. Discovery of CHD1 Antagonists for PTEN-Deficient Prostate Cancer. J Med Chem. 2024 Nov 28;67(22):20056-20075. |