Bioactivity | UK-59811 hydrochloride, a Br-dihydropyridine derivative, is a potent bacterial homotetrameric model voltage-gated Ca2+ (CaV) channel CaVAb inhibitor with an IC50 of 194 nM[1]. |
Target | IC50: 194 nM (CaVAb) |
Name | UK-59811 hydrochloride |
CAS | 2250025-89-7 |
Formula | C22H30BrClN2O5 |
Molar Mass | 517.84 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lin Tang, et al. Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs. Nature. 2016 Sep 1;537(7618):117-121. |