Bioactivity | UGM-IN-3 (compound 10a) is a UDP-galactopyranose mutase (UGM) inhibitor with a Kd of 66 μM. UGM-IN-3 inhibits the growth of Mycobacterium tuberculosis with a MIC value of 6.2 μg/mL[1]. |
Target | Kd: 66 μM (UDP-galactopyranose mutase (UGM))MIC: 6.2 μg/mL (Mycobacterium tuberculosis) |
Name | UGM-IN-3 |
CAS | 2254751-04-5 |
Formula | C18H16INO2 |
Molar Mass | 405.23 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Carine Maaliki, et al. Synthesis and evaluation of heterocycle structures as potential inhibitors of Mycobacterium tuberculosis UGM. Bioorg Med Chem. 2020 Jul 1;28(13):115579. |