| Bioactivity | UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 (PAR4) antagonist (IC50=4 nM; Kd=1.4 nM). UDM-001651 shows antiplatelet potency (IC50=25 nM) in a γ-thrombin-induced platelet-rich plasma aggregation assay (γ-Thr PRP)[1]. |
| Target | IC50: 4 nM (PAR4)Kd: 1.4 nM (PAR4) |
| Name | UDM-001651 |
| CAS | 1477497-01-0 |
| Formula | C28H23N3O5S |
| Molar Mass | 513.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Miller MM, et al. Discovery of Potent Protease-Activated Receptor 4 Antagonists with in vivo Antithrombotic Efficacy. J Med Chem. 2019 Jun 27. |
UDM-001651
CAS: 1477497-01-0 F: C28H23N3O5S W: 513.56
UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 (PAR4) antagonist (IC50=4 nM; K
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