| Bioactivity | UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4[1][2]. | ||||||||||||
| Target | pKi: 10.7 (MT1).pKi: 10.4 (MT2) | ||||||||||||
| Invitro | UCM 608 is a high affinity melatonin membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4 [1]. | ||||||||||||
| Name | UCM 608 | ||||||||||||
| CAS | 151889-03-1 | ||||||||||||
| Formula | C19H20N2O2 | ||||||||||||
| Molar Mass | 308.37 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Radogna F, et al. Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal and tumor leukocytes. Toxicol Appl Pharmacol. 2009;239(1):37-45. [2]. Mor, M., et al. Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands. Bioorganic & Medicinal Chemistry, 9(4), 1045–1057. |