Bioactivity | UCM-13207 (compound 21) is a selective ICMT inhibitor that ameliorates basic progeria-like features. UCM-13207 can improve the survival rate of LmnaG609G/G609G mice in the mouse premature aging model[1]. |
Name | UCM-13207 |
CAS | 1621536-10-4 |
Formula | C24H32N2O2 |
Molar Mass | 380.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Marcos-Ramiro B et al. Isoprenylcysteine carboxylmethyltransferase-based therapy for Hutchinson–Gilford progeria syndrome[J]. ACS Central Science, 2021, 7(8): 1300-1310. |