| Bioactivity | UCL-1848 TFA is a hSK1 blocker with an IC50 value of 1.1 nM. hSK1 is a small conductance calcium-activated potassium channel[1]. |
| Target | IC50: 1.1 nM (hSK1) |
| CAS | 201147-53-7 |
| Formula | C32H34F6N4O4 |
| Molar Mass | 652.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shah M, et al. The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines. Br J Pharmacol. 2000 Feb;129(4):627-30. [2]. Chen JQ, et al. bis-Quinolinium cyclophanes: 8,14-diaza-1,7(1, 4)-diquinolinacyclotetradecaphane (UCL 1848), a highly potent and selective, nonpeptidic blocker of the apamin-sensitive Ca(2+)-activated K(+) channel. J Med Chem. 2000 Sep 21;43(19):3478-81. |
UCL-1848 TFA
CAS: 201147-53-7 F: C32H34F6N4O4 W: 652.63
UCL-1848 TFA is a hSK1 blocker with an IC50 value of 1.1 nM. hSK1 is a small conductance calcium-activated potassium cha
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