| Bioactivity | UBP310 is a selective GluR5 antagonist, with a Kd of 130 nM[1]. | ||||||||||||
| Target | GluR5 | ||||||||||||
| Invitro | UBP310 binds to GluR5 S1S2 with an affinity of 130 nM and shows 12,700-fold selectivity for GluR5 versus GluR6 and 830-fold selectivity for GluR5 versus GluR2[1]. | ||||||||||||
| Name | UBP310 | ||||||||||||
| CAS | 902464-46-4 | ||||||||||||
| Formula | C14H15N3O6S | ||||||||||||
| Molar Mass | 353.35 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Mark L Mayer, et al. Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists. J Neurosci. 2006 Mar 15;26(11):2852-61. |